Mechanism of Action

An important starting point for the discussion of passionflower’s mechanism of action is a review of the communication process between the mood-forming nerve cells in the brain. Nerve cells communicate with each other via messengers (neurotransmitters). One of these is gamma-aminobutyric acid (GABA). An upstream nerve cell releases GABA into the so-called synaptic cleft, which is a space between nerve cells. From here, it travels downstream to the next nerve cell. Subsequently, the messengers are taken up again and inactivated by the upstream nerve cell. GABA acts as a calming and relaxing agent during stressful situations. A deficiency of GABA may lead to sleep disturbances and conditions of anxiety and tension. 


Passionflower extract strengthens GABA’s effectiveness, thereby promoting a state of relaxation.


Video: GABA’s Effects in the Brain